This document is intended for practicing clinicians and other healthcare professionals involved in the holistic care of adult patients with presumptive or confirmed tuberculosis (TB), updating the 2006 Philippine Clinical Practice Guidelines on the Diagnosis, Treatment, Prevention and Control of Tuberculosis. Its timely release comes after the recent revision of the National Tuberculosis Control Program (NTP) Manual of Procedures (MOP) 5th Edition of the Department of Health (DOH), the 2014 International Standards for Tuberculosis Care (ISTC) and recent TB policies and statements released by the World Health Organization (WHO) since 2006.

This document has the following objectives:

1. To update the 2006 Philippine Clinical Practice Guidelines on TB in Adults with recent medical evidence (2005-2015) in light of new developments at the global level, further localized in the Philippine setting, which will serve as useful tool to assist clinicians and other TB personnel to standardize diagnosis and management of TB among adult Filipinos;

2. To harmonize with and complement the NTP-MOP by providing medical evidence to support its policies, with focus on local data where available, in order to facilitate acceptance and compliance among private healthcare providers; and

3. To identify new and relevant TB-related issues and areas for future research in the diagnosis, treatment, prevention and control of TB among immunocompetent and high risk clinical groups in the Philippine setting.